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Pan-cancer analysis reveals cooperativity of both strands of microRNA that regulate tumorigenesis and patient survival

Recently, both 5p and 3p miRNA strands are being recognized as functional instead of only one, leaving many miRNA strands uninvestigated. To determine whether both miRNA strands, which have different mRNA-targeting sequences, cooperate to regulate pathways/functions across cancer types, we evaluate...

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Publicat a:Nat Commun
Autors principals: Mitra, Ramkrishna, Adams, Clare M., Jiang, Wei, Greenawalt, Evan, Eischen, Christine M.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7033124/
https://ncbi.nlm.nih.gov/pubmed/32080184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14713-2
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