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BCL-W has a fundamental role in B cell survival and lymphomagenesis

Compromised apoptotic signaling is a prerequisite for tumorigenesis. The design of effective therapies for cancer treatment depends on a comprehensive understanding of the mechanisms that govern cell survival. The antiapoptotic proteins of the BCL-2 family are key regulators of cell survival and are...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Adams, Clare M., Kim, Annette S., Mitra, Ramkrishna, Choi, John K., Gong, Jerald Z., Eischen, Christine M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5272186/
https://ncbi.nlm.nih.gov/pubmed/28094768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI89486
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