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Abrogated AID function prolongs survival and diminishes renal pathology in the BXSB mouse model of SLE

Almost a decade has passed since the approval of belimumab, a monoclonal antibody directed against B lymphocyte stimulation and the first targeted therapy approved for systemic lupus erythematous (SLE) in over 50 years. While well tolerated, the efficacy of belimumab remains limited and is not label...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Zhu, Jing, Hay, Alayna N, Potter, Ashley A, Richwine, Madison W, Sproule, Thomas, LeRoith, Tanya, Wilson, John, Hasham, Muneer G, Roopenian, Derry C, Leeth, Caroline M
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7033011/
https://ncbi.nlm.nih.gov/pubmed/31988182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900501
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