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Pharmacokinetic comparison between fixed-dose combination of fimasartan/amlodipine 60/10 mg and the corresponding loose combination through partial replicated crossover study in healthy subjects

Combination therapies of antihypertensive drugs are recommended in cases where hypertension is not controlled by monotherapy. This study aimed to compare the pharmacokinetics (PKs) between fixed-dose combination (FDC) of fimasartan/amlodipine 60/10 mg and the corresponding loose combination. Because...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Transl Clin Pharmacol
Hauptverfasser: Yang, Eunsol, Lee, Soyoung, Lee, Heechan, Hwang, Inyoung, Jang, In-Jin, Yu, Kyung-Sang, Lee, SeungHwan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Korean Society for Clinical Pharmacology and Therapeutics 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7032963/
https://ncbi.nlm.nih.gov/pubmed/32095481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12793/tcp.2019.27.4.134
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