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Pharmacokinetic comparison between fixed-dose combination of fimasartan/amlodipine 60/10 mg and the corresponding loose combination through partial replicated crossover study in healthy subjects

Combination therapies of antihypertensive drugs are recommended in cases where hypertension is not controlled by monotherapy. This study aimed to compare the pharmacokinetics (PKs) between fixed-dose combination (FDC) of fimasartan/amlodipine 60/10 mg and the corresponding loose combination. Because...

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Publicado en:Transl Clin Pharmacol
Autores principales: Yang, Eunsol, Lee, Soyoung, Lee, Heechan, Hwang, Inyoung, Jang, In-Jin, Yu, Kyung-Sang, Lee, SeungHwan
Formato: Artigo
Lenguaje:Inglês
Publicado: Korean Society for Clinical Pharmacology and Therapeutics 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7032963/
https://ncbi.nlm.nih.gov/pubmed/32095481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12793/tcp.2019.27.4.134
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