Pharmacokinetic comparison between fixed-dose combination of fimasartan/amlodipine 60/10 mg and the corresponding loose combination through partial replicated crossover study in healthy subjects

Combination therapies of antihypertensive drugs are recommended in cases where hypertension is not controlled by monotherapy. This study aimed to compare the pharmacokinetics (PKs) between fixed-dose combination (FDC) of fimasartan/amlodipine 60/10 mg and the corresponding loose combination. Because...

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Vydáno v:Transl Clin Pharmacol
Hlavní autoři: Yang, Eunsol, Lee, Soyoung, Lee, Heechan, Hwang, Inyoung, Jang, In-Jin, Yu, Kyung-Sang, Lee, SeungHwan
Médium: Artigo
Jazyk:Inglês
Vydáno: Korean Society for Clinical Pharmacology and Therapeutics 2019
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7032963/
https://ncbi.nlm.nih.gov/pubmed/32095481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12793/tcp.2019.27.4.134
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