An IL-15-based superagonist ALT-803 enhances the NK cell response to cetuximab-treated squamous cell carcinoma of the head and neck

Squamous cell carcinoma of the head and neck (SCCHN) is the sixth most common cancer worldwide and epidermal growth factor receptor (EGFR) is overexpressed in greater than 90% of patient tumors. Cetuximab is a monoclonal antibody that binds to EGFR and can activate immune cells, such as natural kill...

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Veröffentlicht in:Cancer Immunol Immunother
Hauptverfasser: Pinette, Ashley, McMichael, Elizabeth, Courtney, Nicholas B., Duggan, Megan, Benner, Brooke N., Choueiry, Fouad, Yu, Lianbo, Abood, David, Mace, Thomas A., Carson, William E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Berlin Heidelberg 2019
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7032639/
https://ncbi.nlm.nih.gov/pubmed/31338557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-019-02372-2
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