An IL-15-based superagonist ALT-803 enhances the NK cell response to cetuximab-treated squamous cell carcinoma of the head and neck

Squamous cell carcinoma of the head and neck (SCCHN) is the sixth most common cancer worldwide and epidermal growth factor receptor (EGFR) is overexpressed in greater than 90% of patient tumors. Cetuximab is a monoclonal antibody that binds to EGFR and can activate immune cells, such as natural kill...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Immunother
Main Authors: Pinette, Ashley, McMichael, Elizabeth, Courtney, Nicholas B., Duggan, Megan, Benner, Brooke N., Choueiry, Fouad, Yu, Lianbo, Abood, David, Mace, Thomas A., Carson, William E.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2019
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7032639/
https://ncbi.nlm.nih.gov/pubmed/31338557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-019-02372-2
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