Novel Anti-Angiogenic PEDF-Derived Small Peptides Mitigate Choroidal Neovascularization

Abnormal migration and proliferation of endothelial cells (EC) drive neovascular retinopathies. While anti-VEGF treatment slows progression, pathology is often supported by decrease in intraocular pigment epithelium-derived factor (PEDF), an endogenous inhibitor of angiogenesis. A surface helical 34...

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Gepubliceerd in:Exp Eye Res
Hoofdauteurs: Sheibani, Nader, Wang, Shoujian, Darjatmoko, Soesiawati R., Fisk, Debra L., Shahi, Pawan K., Patnaik, Bikash R., Sorenson, Christine M., Bhowmick, Reshma, Volpert, Olga V., Albert, Daniel M, Melgar-Asensio, Ignacio, Henkin, Jack
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7032632/
https://ncbi.nlm.nih.gov/pubmed/31520600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2019.107798
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