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Systematically optimized topical delivery system for Loperamide hydrochloride: Formulation design, in vitro and in vivo biopharmaceutical evaluation

This study aimed to develop a suitable topical delivery system containing diethylene glycol monoethyl ether (DGME) for Loperamide hydrochloride (Lop). Two factors, three levels Central-Composite design were applied by generating a quadratic polynomial equation to form contour plots and response surf...

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Detalhes bibliográficos
Publicado no:Asian J Pharm Sci
Main Authors: Shu, Jianhui, Zhao, Jingjing, Guo, Fang
Formato: Artigo
Idioma:Inglês
Publicado em: Shenyang Pharmaceutical University 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7032216/
https://ncbi.nlm.nih.gov/pubmed/32104399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajps.2017.08.009
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