The effect of monosialylganglioside mix modifying the PEGylated liposomal epirubicin on the accelerated blood clearance phenomenon

PEGylated liposomes are potential candidates to improve the pharmacokinetic characteristics of encapsulated drugs, to extend their circulation half-life and facilitate their passive accumulation at tumour sites. However, PEG-modified liposomes can induce accelerated blood clearance (ABC) upon repeat...

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Detalhes bibliográficos
Publicado no:Asian J Pharm Sci
Principais autores: Zhang, Ting, Zhou, Songlei, Kang, Le, Luo, Xiang, Liu, Yang, Song, Yanzhi, Liu, Xinrong, Deng, Yihui
Formato: Artigo
Idioma:Inglês
Publicado em: Shenyang Pharmaceutical University 2017
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Original Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7032097/
https://ncbi.nlm.nih.gov/pubmed/32104322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajps.2016.06.005
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