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The effect of monosialylganglioside mix modifying the PEGylated liposomal epirubicin on the accelerated blood clearance phenomenon

PEGylated liposomes are potential candidates to improve the pharmacokinetic characteristics of encapsulated drugs, to extend their circulation half-life and facilitate their passive accumulation at tumour sites. However, PEG-modified liposomes can induce accelerated blood clearance (ABC) upon repeat...

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Bibliografiske detaljer
Principais autores: Ting Zhang, Songlei Zhou, Le Kang, Xiang Luo, Yang Liu, Yanzhi Song, Xinrong Liu, Yihui Deng
Format: Artigo
Sprog:Inglês
Udgivet: KeAi Communications Co., Ltd. 2017-03-01
Serier:Asian Journal of Pharmaceutical Sciences
Fag:
Online adgang:http://www.sciencedirect.com/science/article/pii/S1818087616300605
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