Mixed PEGylated surfactant modifying system decrease the accelerated blood clearance phenomenon of nanoemulsions in rats

The accelerated blood clearance (ABC) phenomenon which is induced by repeated injection of poly (ethylene glycol) (PEG)-coated colloidal carriers gives clinical challenge to the promising drug delivery system. It is necessary to decrease this unexpected immunological response. A novel 4-arm poly (et...

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Bibliographische Detailangaben
Veröffentlicht in:Asian J Pharm Sci
Hauptverfasser: Su, Yuqing, Tang, Wenya, Song, Yanzhi, Wang, Chunling, Tian, Qingjing, Wang, Xuling, Quan, Jingjing, Li, Buoqun, Wang, Shaoning, Deng, Yihui
Format: Artigo
Sprache:Inglês
Veröffentlicht: Shenyang Pharmaceutical University 2017
Schlagworte:
Original Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7032248/
https://ncbi.nlm.nih.gov/pubmed/32104311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajps.2016.07.003
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