Platelet IP6K1 regulates neutrophil extracellular trap-microparticle complex formation in acute pancreatitis

Platelet inositol hexakisphosphate kinase 1 (IP6K1) has been shown to control systemic inflammation. Herein, we examined if platelets and IP6K1 regulate pancreatic tissue injury via formation of NETs in experimental models of acute pancreatitis (AP) in mice. By use of electron microscopy abundant NE...

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Bibliografiska uppgifter
I publikationen:JCI Insight
Huvudupphovsmän: Madhi, Raed, Rahman, Milladur, Taha, Dler, Linders, Johan, Merza, Mohammed, Wang, Yongzhi, Mörgelin, Matthias, Thorlacius, Henrik
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2019
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7032015/
https://ncbi.nlm.nih.gov/pubmed/31593553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.129270
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