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Platelet IP6K1 regulates neutrophil extracellular trap-microparticle complex formation in acute pancreatitis

Platelet inositol hexakisphosphate kinase 1 (IP6K1) has been shown to control systemic inflammation. Herein, we examined if platelets and IP6K1 regulate pancreatic tissue injury via formation of NETs in experimental models of acute pancreatitis (AP) in mice. By use of electron microscopy abundant NE...

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Podrobná bibliografie
Vydáno v:JCI Insight
Hlavní autoři: Madhi, Raed, Rahman, Milladur, Taha, Dler, Linders, Johan, Merza, Mohammed, Wang, Yongzhi, Mörgelin, Matthias, Thorlacius, Henrik
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7032015/
https://ncbi.nlm.nih.gov/pubmed/31593553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.129270
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