Platelet IP6K1 regulates neutrophil extracellular trap-microparticle complex formation in acute pancreatitis

Platelet inositol hexakisphosphate kinase 1 (IP6K1) has been shown to control systemic inflammation. Herein, we examined if platelets and IP6K1 regulate pancreatic tissue injury via formation of NETs in experimental models of acute pancreatitis (AP) in mice. By use of electron microscopy abundant NE...

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Bibliografske podrobnosti
izdano v:JCI Insight
Main Authors: Madhi, Raed, Rahman, Milladur, Taha, Dler, Linders, Johan, Merza, Mohammed, Wang, Yongzhi, Mörgelin, Matthias, Thorlacius, Henrik
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2019
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7032015/
https://ncbi.nlm.nih.gov/pubmed/31593553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.129270
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