Role of l- and d-Menthol in the Glucuronidation and Detoxification of the Major Lung Carcinogen, NNAL

Menthol, which creates mint flavor and scent, is often added to tobacco in both menthol and nonmenthol cigarettes. A potent tobacco carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), is extensively metabolized to its equally carcinogenic metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-...

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Veröffentlicht in:Drug Metab Dispos
Hauptverfasser: Kozlovich, Shannon, Chen, Gang, Watson, Christy J.W., Blot, William J., Lazarus, Philip
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Pharmacology and Experimental Therapeutics 2019
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7031765/
https://ncbi.nlm.nih.gov/pubmed/31578206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.119.088351
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