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The effect of phage genetic diversity on bacterial resistance evolution

CRISPR-Cas adaptive immune systems are found in bacteria and archaea and provide defence against phage by inserting phage-derived sequences into CRISPR loci on the host genome to provide sequence specific immunological memory against re-infection. Under laboratory conditions the bacterium Pseudomona...

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Detalhes bibliográficos
Publicado no:ISME J
Main Authors: Broniewski, Jenny M., Meaden, Sean, Paterson, Steve, Buckling, Angus, Westra, Edze R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7031251/
https://ncbi.nlm.nih.gov/pubmed/31896785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41396-019-0577-7
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