Engineering light-controllable CAR T cells for cancer immunotherapy

T cells engineered to express chimeric antigen receptors (CARs) can recognize and engage with target cancer cells with redirected specificity for cancer immunotherapy. However, there is a lack of ideal CARs for solid tumor antigens, which may lead to severe adverse effects. Here, we developed a ligh...

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Publicat a:Sci Adv
Autors principals: Huang, Ziliang, Wu, Yiqian, Allen, Molly E., Pan, Yijia, Kyriakakis, Phillip, Lu, Shaoying, Chang, Ya-Ju, Wang, Xin, Chien, Shu, Wang, Yingxiao
Format: Artigo
Idioma:Inglês
Publicat: American Association for the Advancement of Science 2020
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7030928/
https://ncbi.nlm.nih.gov/pubmed/32128416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aay9209
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