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Tacrolimus- and sirolimus-induced human β cell dysfunction is reversible and preventable
Posttransplantation diabetes mellitus (PTDM) is a common and significant complication related to immunosuppressive agents required to prevent organ or cell transplant rejection. To elucidate the effects of 2 commonly used agents, the calcineurin inhibitor tacrolimus (TAC) and the mTOR inhibitor siro...
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| Опубликовано в: : | JCI Insight |
|---|---|
| Главные авторы: | , , , , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Clinical Investigation
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7030815/ https://ncbi.nlm.nih.gov/pubmed/31941840 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.130770 |
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