Tacrolimus- and sirolimus-induced human β cell dysfunction is reversible and preventable

Posttransplantation diabetes mellitus (PTDM) is a common and significant complication related to immunosuppressive agents required to prevent organ or cell transplant rejection. To elucidate the effects of 2 commonly used agents, the calcineurin inhibitor tacrolimus (TAC) and the mTOR inhibitor siro...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:JCI Insight
Hauptverfasser: Dai, Chunhua, Walker, John T., Shostak, Alena, Padgett, Ana, Spears, Erick, Wisniewski, Scott, Poffenberger, Greg, Aramandla, Radhika, Dean, E. Danielle, Prasad, Nripesh, Levy, Shawn E., Greiner, Dale L., Shultz, Leonard D., Bottino, Rita, Powers, Alvin C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7030815/
https://ncbi.nlm.nih.gov/pubmed/31941840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.130770
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge