USP27X negatively regulates antiviral signaling by deubiquitinating RIG-I

RIG-I plays important roles in pathogen sensing and activation of antiviral innate immune responses in response to RNA viruses. RIG-I-mediated signaling must be precisely controlled to maintain innate immune signaling homeostasis. Previous studies demonstrated that lysine 63 (K63)-linked polyubiquit...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Pathog
Prif Awduron: Tao, Xinyue, Chu, Bei, Xin, Di, Li, Lin, Sun, Qinmiao
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2020
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7029883/
https://ncbi.nlm.nih.gov/pubmed/32027733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008293
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