Improvements in Metabolic Syndrome by Xanthohumol Derivatives are Linked to Altered Gut Microbiota and Bile Acid Metabolism

SCOPE: We previously showed that two hydrogenated xanthohumol (XN) derivatives, α,β-dihydro-XN (DXN) and tetrahydro-XN (TXN), improved parameters of metabolic syndrome (MetS), a critical risk factor of cardiovascular disease (CVD) and type 2 diabetes, in a diet-induced obese murine model. We hypothe...

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Publicado no:Mol Nutr Food Res
Main Authors: Zhang, Yang, Bobe, Gerd, Revel, Johana S., Rodrigues, Richard, Sharpton, Thomas J., Fantacone, Mary L., Raslan, Kareem, Miranda, Cristobal L., Lowry, Malcolm B., Blakemore, Paul R., Morgun, Andrey, Shulzhenko, Natalia, Maier, Claudia S., Stevens, Jan F., Gombart, Adrian F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7029812/
https://ncbi.nlm.nih.gov/pubmed/31755244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mnfr.201900789
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