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Stereodivergent, chemoenzymatic synthesis of azaphilone natural products.

Selective access to a targeted isomer is often critical in the synthesis of biologically active molecules. Whereas small-molecule reagents and catalysts often act with anticipated site- and stereoselectivity, this predictability does not extend to enzymes. Further, the lack of access to catalysts th...

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Détails bibliographiques
Publié dans:J Am Chem Soc
Auteurs principaux: Pyser, Joshua B., Baker Dockrey, Summer A., Benítez, Attabey Rodríguez, Joyce, Leo A., Wiscons, Ren A., Smith, Janet L., Narayan, Alison R. H.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7029798/
https://ncbi.nlm.nih.gov/pubmed/31692339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b09385
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