Accelerated Hyper-Maturation of Parvalbumin Circuits in the Absence of MeCP2

Methyl-CpG-binding protein 2 (MeCP2) mutations are the primary cause of Rett syndrome, a severe neurodevelopmental disorder. Cortical parvalbumin GABAergic interneurons (PV) make exuberant somatic connections onto pyramidal cells in the visual cortex of Mecp2-deficient mice, which contributes to sil...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cereb Cortex
Prif Awduron: Patrizi, Annarita, Awad, Patricia N, Chattopadhyaya, Bidisha, Li, Chloe, Di Cristo, Graziella, Fagiolini, Michela
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2020
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7029683/
https://ncbi.nlm.nih.gov/pubmed/31038696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhz085
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