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Accelerated Hyper-Maturation of Parvalbumin Circuits in the Absence of MeCP2

Methyl-CpG-binding protein 2 (MeCP2) mutations are the primary cause of Rett syndrome, a severe neurodevelopmental disorder. Cortical parvalbumin GABAergic interneurons (PV) make exuberant somatic connections onto pyramidal cells in the visual cortex of Mecp2-deficient mice, which contributes to sil...

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Bibliografske podrobnosti
izdano v:Cereb Cortex
Main Authors: Patrizi, Annarita, Awad, Patricia N, Chattopadhyaya, Bidisha, Li, Chloe, Di Cristo, Graziella, Fagiolini, Michela
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7029683/
https://ncbi.nlm.nih.gov/pubmed/31038696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhz085
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