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Analysis of Dot/Icm Type IVB Secretion System Subassemblies by Cryoelectron Tomography Reveals Conformational Changes Induced by DotB Binding

Type IV secretion systems (T4SSs) are sophisticated nanomachines used by many bacterial pathogens to translocate protein and DNA substrates across a host cell membrane. Although T4SSs have important roles in promoting bacterial infections, little is known about the biogenesis of the apparatus and th...

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Publicat a:mBio
Autors principals: Park, Donghyun, Chetrit, David, Hu, Bo, Roy, Craig R., Liu, Jun
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7029142/
https://ncbi.nlm.nih.gov/pubmed/32071271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.03328-19
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