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Analysis of Dot/Icm Type IVB Secretion System Subassemblies by Cryoelectron Tomography Reveals Conformational Changes Induced by DotB Binding

Type IV secretion systems (T4SSs) are sophisticated nanomachines used by many bacterial pathogens to translocate protein and DNA substrates across a host cell membrane. Although T4SSs have important roles in promoting bacterial infections, little is known about the biogenesis of the apparatus and th...

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Bibliographische Detailangaben
Veröffentlicht in:mBio
Hauptverfasser: Park, Donghyun, Chetrit, David, Hu, Bo, Roy, Craig R., Liu, Jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7029142/
https://ncbi.nlm.nih.gov/pubmed/32071271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.03328-19
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