Dot/Icm Type IVB Secretion System Requirements for Coxiella burnetii Growth in Human Macrophages

Central to Q fever pathogenesis is replication of the causative agent, Coxiella burnetii, within a phagolysosome-like parasitophorous vacuole (PV) in mononuclear phagocytes. C. burnetii modulates PV biogenesis and other host cell functions, such as apoptotic signaling, presumably via the activity of...

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Autori principali: Beare, Paul A., Gilk, Stacey D., Larson, Charles L., Hill, Joshua, Stead, Christopher M., Omsland, Anders, Cockrell, Diane C., Howe, Dale, Voth, Daniel E., Heinzen, Robert A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Microbiology 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3163939/
https://ncbi.nlm.nih.gov/pubmed/21862628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00175-11
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