Microsatellite instability screening in colorectal adenomas to detect Lynch syndrome patients? A systematic review and meta-analysis

The colorectal cancer spectrum has changed due to population screening programs, with a shift toward adenomas and early cancers. Whether it would be a feasible option to test these adenomas for detection of Lynch syndrome (LS) patients is unclear. Through meta-analysis and systematic review, risk fa...

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Dettagli Bibliografici
Pubblicato in:Eur J Hum Genet
Autori principali: Dabir, Parag D., Bruggeling, Carlijn E., van der Post, Rachel S., Dutilh, Bas E., Hoogerbrugge, Nicoline, Ligtenberg, Marjolijn J. L., Boleij, Annemarie, Nagtegaal, Iris D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer International Publishing 2019
Soggetti:
Review Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7028913/
https://ncbi.nlm.nih.gov/pubmed/31695176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41431-019-0538-7
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