Opportunities for immunotherapy in microsatellite instable colorectal cancer

Microsatellite instability (MSI), the somatic accumulation of length variations in repetitive DNA sequences called microsatellites, is frequently observed in both hereditary and sporadic colorectal cancer (CRC). It has been established that defects in the DNA mismatch repair (MMR) pathway underlie t...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Immunother
Main Authors: Westdorp, Harm, Fennemann, Felix L., Weren, Robbert D. A., Bisseling, Tanya M., Ligtenberg, Marjolijn J. L., Figdor, Carl G., Schreibelt, Gerty, Hoogerbrugge, Nicoline, Wimmers, Florian, de Vries, I. Jolanda M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2016
Assuntos:
Focussed Research Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035655/
https://ncbi.nlm.nih.gov/pubmed/27060000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-016-1832-7
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