Opportunities for immunotherapy in microsatellite instable colorectal cancer

Microsatellite instability (MSI), the somatic accumulation of length variations in repetitive DNA sequences called microsatellites, is frequently observed in both hereditary and sporadic colorectal cancer (CRC). It has been established that defects in the DNA mismatch repair (MMR) pathway underlie t...

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Dettagli Bibliografici
Pubblicato in:Cancer Immunol Immunother
Autori principali: Westdorp, Harm, Fennemann, Felix L., Weren, Robbert D. A., Bisseling, Tanya M., Ligtenberg, Marjolijn J. L., Figdor, Carl G., Schreibelt, Gerty, Hoogerbrugge, Nicoline, Wimmers, Florian, de Vries, I. Jolanda M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2016
Soggetti:
Focussed Research Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035655/
https://ncbi.nlm.nih.gov/pubmed/27060000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-016-1832-7
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