PTEN Hamartoma Tumor Syndrome and Immune Dysregulation()()()

Carriers of a pathogenic germline mutations in the PTEN gene, a well-known tumor suppressor gene, are at increased risk of multiple benign and malignant tumors, e.g. breast, thyroid, endometrial and colon cancer. This is called PTEN Hamartomous Tumor Syndrome (PHTS). PHTS patients may also have an i...

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Detalhes bibliográficos
Publicado no:Transl Oncol
Main Authors: Eissing, Marc, Ripken, Lise, Schreibelt, Gerty, Westdorp, Harm, Ligtenberg, Marjolijn, Netea-Maier, Romana, Netea, Mihai G., de Vries, I. Jolanda M., Hoogerbrugge, Nicoline
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2018
Assuntos:
Review article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6277246/
https://ncbi.nlm.nih.gov/pubmed/30504085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2018.11.003
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