PTEN Hamartoma Tumor Syndrome and Immune Dysregulation()()()

Carriers of a pathogenic germline mutations in the PTEN gene, a well-known tumor suppressor gene, are at increased risk of multiple benign and malignant tumors, e.g. breast, thyroid, endometrial and colon cancer. This is called PTEN Hamartomous Tumor Syndrome (PHTS). PHTS patients may also have an i...

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Bibliographic Details
Published in:Transl Oncol
Main Authors: Eissing, Marc, Ripken, Lise, Schreibelt, Gerty, Westdorp, Harm, Ligtenberg, Marjolijn, Netea-Maier, Romana, Netea, Mihai G., de Vries, I. Jolanda M., Hoogerbrugge, Nicoline
Format: Artigo
Language:Inglês
Published: Neoplasia Press 2018
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Review article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6277246/
https://ncbi.nlm.nih.gov/pubmed/30504085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2018.11.003
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