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Two‐day‐treatment of Activin‐A leads to transient change in SV‐HFO osteoblast gene expression and reduction in matrix mineralization

Activins regulate bone formation by controlling osteoclasts and osteoblasts. We investigated Activin‐A mechanism of action on human osteoblast mineralization, RNA and microRNA (miRNA) expression profile. A single 2‐day treatment of Activin‐A at Day 5 of osteoblast differentiation significantly reduc...

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Bibliografiske detaljer
Udgivet i:J Cell Physiol
Main Authors: Baroncelli, Marta, Drabek, Ksenija, Eijken, Marco, van der Eerden, Bram C. J., van de Peppel, Jeroen, van Leeuwen, Johannes P. T. M.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7028110/
https://ncbi.nlm.nih.gov/pubmed/31667867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.29365
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