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Two‐day‐treatment of Activin‐A leads to transient change in SV‐HFO osteoblast gene expression and reduction in matrix mineralization

Activins regulate bone formation by controlling osteoclasts and osteoblasts. We investigated Activin‐A mechanism of action on human osteoblast mineralization, RNA and microRNA (miRNA) expression profile. A single 2‐day treatment of Activin‐A at Day 5 of osteoblast differentiation significantly reduc...

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Detalhes bibliográficos
Publicado no:J Cell Physiol
Main Authors: Baroncelli, Marta, Drabek, Ksenija, Eijken, Marco, van der Eerden, Bram C. J., van de Peppel, Jeroen, van Leeuwen, Johannes P. T. M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7028110/
https://ncbi.nlm.nih.gov/pubmed/31667867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.29365
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