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Sharing DNA-binding information across structurally similar proteins enables accurate specificity determination

We are now in an era where protein–DNA interactions have been experimentally assayed for thousands of DNA-binding proteins. In order to infer DNA-binding specificities from these data, numerous sophisticated computational methods have been developed. These approaches typically infer DNA-binding spec...

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Bibliographische Detailangaben
Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Wetzel, Joshua L, Singh, Mona
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7028011/
https://ncbi.nlm.nih.gov/pubmed/31777934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz1087
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