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DIP-chip: Rapid and accurate determination of DNA-binding specificity
We have developed a new method for determining the DNA-binding specificity of proteins. In DIP-chip (DNA immunoprecipitation with microarray detection), protein·DNA complexes are isolated from an in vitro mixture of purified protein and naked genomic DNA. Whole-genome DNA microarrays are used to ide...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cold Spring Harbor Laboratory Press
2005
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC551568/ https://ncbi.nlm.nih.gov/pubmed/15710749 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.3256505 |
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