DIP-chip: Rapid and accurate determination of DNA-binding specificity

We have developed a new method for determining the DNA-binding specificity of proteins. In DIP-chip (DNA immunoprecipitation with microarray detection), protein·DNA complexes are isolated from an in vitro mixture of purified protein and naked genomic DNA. Whole-genome DNA microarrays are used to ide...

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Bibliografiske detaljer
Main Authors: Liu, Xiao, Noll, David M., Lieb, Jason D., Clarke, Neil D.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2005
Fag:
Methods
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC551568/
https://ncbi.nlm.nih.gov/pubmed/15710749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.3256505
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