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Divalent cations promote TALE DNA-binding specificity
Recent advances in gene editing have been enabled by programmable nucleases such as transcription activator-like effector nucleases (TALENs) and CRISPR–Cas9. However, several open questions remain regarding the molecular machinery in these systems, including fundamental search and binding behavior a...
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| 發表在: | Nucleic Acids Res |
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| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7026652/ https://ncbi.nlm.nih.gov/pubmed/31863586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz1174 |
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