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Cryo-EM Structures of the Ionotropic Glutamate Receptor GluD1 Reveal a Non-Swapped Architecture

Ionotropic orphan delta receptors (GluD) are not gated by glutamate or any other endogenous ligand but are grouped with ionotropic glutamate receptors based on sequence similarity. GluD1 receptors play critical roles in synaptogenesis, synapse maintenance and have been implicated in neuronal disorde...

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Detalhes bibliográficos
Publicado no:Nat Struct Mol Biol
Main Authors: Burada, Ananth Prasad, Vinnakota, Rajesh, Kumar, Janesh
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7025878/
https://ncbi.nlm.nih.gov/pubmed/31925409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-019-0359-y
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