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D-serine potently drives ligand-binding domain closure in the ionotropic glutamate receptor GluD2
Despite their classification as ionotropic glutamate receptors, GluD receptors are not functional ligand-gated ion channels and do not bind glutamate. GluD2 receptors bind D-serine and coordinate trans-synaptic complexes that regulate synaptic plasticity. Instead of opening the ion channel pore, mec...
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| Publicado no: | Structure |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7544663/ https://ncbi.nlm.nih.gov/pubmed/32735769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2020.07.005 |
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