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Probing the ionotropic activity of glutamate GluD2 receptor in HEK cells with genetically-engineered photopharmacology

Glutamate delta (GluD) receptors belong to the ionotropic glutamate receptor family, yet they don’t bind glutamate and are considered orphan. Progress in defining the ion channel function of GluDs in neurons has been hindered by a lack of pharmacological tools. Here, we used a chemo-genetic approach...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Lemoine, Damien, Mondoloni, Sarah, Tange, Jérome, Lambolez, Bertrand, Faure, Philippe, Taly, Antoine, Tricoire, Ludovic, Mourot, Alexandre
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7679134/
https://ncbi.nlm.nih.gov/pubmed/33112237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.59026
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