Wordt geladen...
Design and Catalyzed Activation of Tak-242 Prodrugs for Localized Inhibition of TLR4-Induced Inflammation
[Image: see text] Tak-242 (resatorvid), a Toll-like Receptor 4 (TLR4) inhibitor, has been identified as a potent suppressor of innate inflammation. As a strategy to target Tak-242 to select tissue, four TLR4-inactive prodrugs were synthesized for activation via two different release mechanisms. Two...
Bewaard in:
| Gepubliceerd in: | ACS Med Chem Lett |
|---|---|
| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Chemical
Society
2020
|
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7025376/ https://ncbi.nlm.nih.gov/pubmed/32071680 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.9b00518 |
| Tags: |
Voeg label toe
Geen labels, Wees de eerste die dit record labelt!
|