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TLR4 inhibitor TAK-242 attenuates the adverse neural effects of diet-induced obesity
BACKGROUND: Obesity exerts negative effects on brain health, including decreased neurogenesis, impaired learning and memory, and increased risk for Alzheimer’s disease and related dementias. Because obesity promotes glial activation, chronic neuroinflammation, and neural injury, microglia are implic...
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| Publicado no: | J Neuroinflammation |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6217784/ https://ncbi.nlm.nih.gov/pubmed/30396359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1340-0 |
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