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Knockdown of HMGB1 Suppresses Hypoxia-Induced Mitochondrial Biogenesis in Pancreatic Cancer Cells

PURPOSE: To explore the regulatory effect of HMGB1 upon hypoxia-induced mitochondrial biogenesis in pancreatic cancer PANC1/CFPAC1 cells. METHODS: After a down-regulation of HMGB1 expression by lentivirus-mediated RNAi, the effect of knocking down HMGB1 on hypoxia-induced mitochondrial biogenesis wa...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Yang, Liangchun, Ye, Fanghua, Zeng, Li, Li, Yanling, Chai, Wenwen
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7025163/
https://ncbi.nlm.nih.gov/pubmed/32103987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S234530
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