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L‐cysteine/cystathionine‐β‐synthase‐induced relaxation in mouse aorta involves a L‐serine/sphingosine‐1‐phosphate/NO pathway

BACKGROUND AND PURPOSE: Among the three enzymes involved in the transsulfuration pathway, only cystathionine β‐synthase (CBS) converts L‐cysteine into L‐serine and H(2)S. L‐serine is also involved in the de novo sphingolipid biosynthesis through a condensation with palmitoyl‐CoA by the action of ser...

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Dettagli Bibliografici
Pubblicato in:Br J Pharmacol
Autori principali: Mitidieri, Emma, Gurgone, Danila, Caiazzo, Elisabetta, Tramontano, Teresa, Cicala, Carla, Sorrentino, Raffaella, d'Emmanuele di Villa Bianca, Roberta
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7024702/
https://ncbi.nlm.nih.gov/pubmed/30835815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14654
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