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L‐cysteine/cystathionine‐β‐synthase‐induced relaxation in mouse aorta involves a L‐serine/sphingosine‐1‐phosphate/NO pathway
BACKGROUND AND PURPOSE: Among the three enzymes involved in the transsulfuration pathway, only cystathionine β‐synthase (CBS) converts L‐cysteine into L‐serine and H(2)S. L‐serine is also involved in the de novo sphingolipid biosynthesis through a condensation with palmitoyl‐CoA by the action of ser...
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| Опубликовано в: : | Br J Pharmacol |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
John Wiley and Sons Inc.
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7024702/ https://ncbi.nlm.nih.gov/pubmed/30835815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14654 |
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