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Urothelium muscarinic activation phosphorylates CBS(Ser227) via cGMP/PKG pathway causing human bladder relaxation through H(2)S production
The urothelium modulates detrusor activity through releasing factors whose nature has not been clearly defined. Here we have investigated the involvement of H(2)S as possible mediator released downstream following muscarinic (M) activation, by using human bladder and urothelial T24 cell line. Carbac...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4980605/ https://ncbi.nlm.nih.gov/pubmed/27509878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31491 |
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