Urothelium muscarinic activation phosphorylates CBS(Ser227) via cGMP/PKG pathway causing human bladder relaxation through H(2)S production

The urothelium modulates detrusor activity through releasing factors whose nature has not been clearly defined. Here we have investigated the involvement of H(2)S as possible mediator released downstream following muscarinic (M) activation, by using human bladder and urothelial T24 cell line. Carbac...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: d’Emmanuele di Villa Bianca, Roberta, Mitidieri, Emma, Fusco, Ferdinando, Russo, Annapina, Pagliara, Valentina, Tramontano, Teresa, Donnarumma, Erminia, Mirone, Vincenzo, Cirino, Giuseppe, Russo, Giulia, Sorrentino, Raffaella
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980605/
https://ncbi.nlm.nih.gov/pubmed/27509878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31491
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