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Murine Oviductal High-grade Serous Carcinomas Mirror the Genomic Alterations, Gene Expression Profiles and Immune Microenvironment of Their Human Counterparts

Robust pre-clinical models of ovarian high-grade serous carcinoma (HGSC) are needed to advance our understanding of HGSC pathogenesis and to test novel strategies aimed at improving clinical outcomes for women with the disease. Genetically engineered mouse models of HGSC recapitulating the likely ce...

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Dades bibliogràfiques
Publicat a:Cancer Res
Autors principals: McCool, Kevin, Freeman, Zachary T., Zhai, Yali, Wu, Rong, Hu, Kevin, Liu, Chia-Jen, Tomlins, Scott A., Fearon, Eric R., Magnuson, Brian, Kuick, Rork, Cho, Kathleen R.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7024672/
https://ncbi.nlm.nih.gov/pubmed/31806642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-2558
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