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Murine Oviductal High-grade Serous Carcinomas Mirror the Genomic Alterations, Gene Expression Profiles and Immune Microenvironment of Their Human Counterparts

Robust pre-clinical models of ovarian high-grade serous carcinoma (HGSC) are needed to advance our understanding of HGSC pathogenesis and to test novel strategies aimed at improving clinical outcomes for women with the disease. Genetically engineered mouse models of HGSC recapitulating the likely ce...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: McCool, Kevin, Freeman, Zachary T., Zhai, Yali, Wu, Rong, Hu, Kevin, Liu, Chia-Jen, Tomlins, Scott A., Fearon, Eric R., Magnuson, Brian, Kuick, Rork, Cho, Kathleen R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7024672/
https://ncbi.nlm.nih.gov/pubmed/31806642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-2558
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