High-grade serous carcinomas arise in the mouse oviduct via defects linked to the human disease

Recent studies suggest that the most common and lethal type of “ovarian” cancer, high-grade serous carcinoma (HGSC), usually arises from epithelium on the fallopian tube fimbriae, and not from the ovarian surface epithelium (OSE). We have developed Ovgp1-iCreER(T2) mice in which the Ovgp1 promoter c...

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Udgivet i:J Pathol
Main Authors: Zhai, Yali, Wu, Rong, Kuick, Rork, Sessine, Michael S., Schulman, Stephanie, Green, Megan, Fearon, Eric R., Cho, Kathleen R.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568969/
https://ncbi.nlm.nih.gov/pubmed/28608929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4927
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